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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
11.52
Human Site:
S355
Identified Species:
21.11
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
S355
S
G
S
F
M
D
D
S
A
M
H
I
P
P
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
H357
D
S
F
L
D
D
H
H
L
S
R
P
H
P
E
Dog
Lupus familis
XP_546691
722
81319
S525
T
G
S
F
M
D
D
S
T
M
H
I
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
S355
S
G
S
F
M
D
D
S
A
M
H
I
P
P
G
Rat
Rattus norvegicus
Q09137
552
62239
M355
T
G
S
F
M
D
D
M
A
M
H
I
P
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
H326
D
S
F
L
D
D
H
H
L
S
R
P
H
P
E
Chicken
Gallus gallus
Q9IA88
798
88848
S432
N
G
L
F
R
N
R
S
I
S
P
S
S
L
L
Frog
Xenopus laevis
NP_001088426
560
64038
P366
D
S
F
M
E
D
P
P
I
A
R
P
H
P
E
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
M449
A
M
A
R
Y
L
S
M
R
R
H
T
V
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
L323
G
G
D
P
H
D
Q
L
A
I
A
Y
H
L
I
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
P423
E
E
F
Y
Q
V
T
P
N
K
G
P
G
P
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
G346
R
N
R
T
Q
N
D
G
T
V
T
Y
Y
L
I
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
S413
L
D
T
F
L
S
Q
S
P
P
T
F
Q
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
13.3
86.6
N.A.
100
86.6
N.A.
13.3
20
13.3
6.6
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
100
N.A.
13.3
93.3
N.A.
100
93.3
N.A.
13.3
33.3
13.3
20
N.A.
N.A.
26.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
31
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
8
8
0
16
62
39
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
24
% E
% Phe:
0
0
31
47
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
47
0
0
0
0
0
8
0
0
8
0
8
8
31
% G
% His:
0
0
0
0
8
0
16
16
0
0
39
0
31
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
16
8
0
31
0
0
16
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
8
16
8
8
0
8
16
0
0
0
0
24
8
% L
% Met:
0
8
0
8
31
0
0
16
0
31
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
16
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
16
8
8
8
31
31
62
0
% P
% Gln:
0
0
0
0
16
0
16
0
0
0
0
0
8
8
8
% Q
% Arg:
8
0
8
8
8
0
8
0
8
8
24
0
0
0
0
% R
% Ser:
16
24
31
0
0
8
8
39
0
24
0
8
8
0
0
% S
% Thr:
16
0
8
8
0
0
8
0
16
0
16
8
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
0
16
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _